Are we Hardwired?

Table of Contents
Are We Hardwired?


Chapter One Mirror, Mirror…
Twins and the genetics of human personality; the biology of twins; the Minnesota Twin Study; nature vs. nurture; preliminary discussion of genes and behavior
Chapter TwoIn The Beginning: The evolutionary origins of behavior
Behavior in Paramecia; intro to genes and mutations; ion channel genes underlying behavioral mutants in paramecia
Chapter ThreeThe Nose Knows
Pheromones in animals and humans; McClintock; H2 and HLA;
Chapter Four As The Worm Turns: Learning and memory in the roundworm C. elegans
Intro to C. elegans; organization of nervous systems; neurotransmitters; the lrn-1 and lrn-2 genes
Chapter FiveMore About Genes…
Housekeeping vs. special function genes; dominant and recessive genes; pleiotropy; monogenic vs. quantitative genetic traits; genes and the environment
Chapter Six Life in the Fourth Dimension: The role of clocks in regulating behavior
frq in Neurospora; per and tim in Drosophila; per etc in mammals; the SCN; basic nature of mammalian oscillators; circadian disorders in humans; light gathering for clocks.
Chapter Seven You Must Remember This: The evolution of learning and memory.
Aplysia and cAMP; Dunce gene in flies re: learning and mating behavior; cAMP and PDE-4 in neurons; dunce in rats and humans; learning vs. depression; housekeeping genes and brain function.
Chapter Eight The Role of Neurotransmitters in Human Behavior: Depression and Impulsivity
The noradrenergic and serotonin systems; depression; definitions of impulsive behavior; chemical pathways involved in impulsivity; genetic variation in neurotransmitter function; genes vs. environment.
Chapter Nine The Genetics of Aggression
Forms of aggression; nature and heritability of aggression in mice; testosterone and serotonin; serenics in mice and humans
Chapter Ten The Genetics of Consumption, Part I. Eating disorders
Overeating, anorexia and bulimia; heritability of BMI; the leptin system in mice and humans; the role of neurotransmitters; eating disorders as impulsive behaviors; lessons of the Pima indians; genes vs. environment.
Chapter Eleven The Genetics of Consumption, Part II. Alcoholism and drug abuse
The nature of addiction; withdrawal, tolerance; opiates and endorphins; cocaine; alcohol; role of neurotansmitter systems; genetic and environmental influences.
Chapter Twelve The Genetics of Human Mental Function
Variability in mental function; the problem of IQ and intelligence; heritability of human mental fn; history of eugenics; testing mental function; twin studies; role of the environment; genes involved in mental function..
Chapter Thirteen The Genetics of Human Sexual Preference
Family and twin studies; Hamer's X-linked QTL; possible mechanisms
Chapter FourteenGenetics, The Environment, and Free Will
Appendix I - Finding and Identifying genes
Appendix II - A Brief History of Eugenics


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