| Chapter 1 | Aging and Senescence |
| Chapter 2 | The Nature of Cellular Death |
| Chapter 3 | The Evolution of Senescence and Lifespan |
| Chapter 4 | Of Embryos and Worms and Very Old Men: The Developmental Genetics of Senescence and Lifespan |
| Chapter 5 | Human Genetic Diseases That Mimic the Aging Process |
| Chapter 6 | Cycling to Senescence |
| Chapter 7 | Replicative Immortality: Cancer and Aging |
| Chapter 8 | Caloric Restriction and Maximum Possible Lifespan |
| Chapter 9 | Oxidative Stress and Cellular Senescence |
| Chapter 10 | The Aging Brain |
| Chapter 11 | A Conditional Benefit |